Intrinsic catalase dot blot immunoassay for identification of Mycobacterium tuberculosis, Mycobacterium avium, and Mycobacterium intracellulare

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Intrinsic catalase dot blot immunoassay for identification of Mycobacterium tuberculosis, Mycobacterium avium, and Mycobacterium intracellulare.

The heat-labile T class of mycobacterial catalase exhibits peroxidase activity with some substrates. Most species of mycobacteria produce T-catalase, which is serologically characterized by a combination of shared epitopes and unique, species-specific epitopes. Antibodies to T-catalases from Mycobacterium tuberculosis, Mycobacterium avium, and Mycobacterium intracellulare have been cross absorb...

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Mycobacterium Avium-intracellulare Sinusitis.

M ycobacterium avium-intracellulare (MAI) sinusitis is rarely diagnosed. There are only nine previous cases documented in the literature, most of which are in patients with acquired immune deficiency syndrome (AIDS). Awareness of MAI sinusitis may prove valuable to the practicing otolaryngologist, and an elevated index of suspicion is necessary in all immunocompromised patients with sinusitis, ...

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Evaluation of acridinium-ester-labeled DNA probes for identification of Mycobacterium tuberculosis and Mycobacterium avium-Mycobacterium intracellulare complex in culture.

The detectability of mycobacteria in culture by the use of nonisotopic, chemiluminescent DNA probes for Mycobacterium tuberculosis and the M. avium-M. intracellulare complex (MAC) was evaluated and compared with that by the use of 125I-labeled DNA probes for the same mycobacteria. In the assay, rRNA-directed DNA probes labeled with acridinium ester (AE-DNA probes) were used. Unhybridized probes...

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Arylsulfatase activity for differentiating Mycobacterium avium and Mycobacterium intracellulare.

Arylsulfatase activities (96-h reaction) of various strains of Mycobacterium avium and M. intracellulare, as identified by a DNA probe test, were measured. The enzyme activities of M. avium strains were significantly lower [corrected] than those of M. intracellulare strains (P less than 0.005 to P less than 0.025). The enzyme activities did not vary with serovar; that is, the activities of sero...

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Detection of a novel catalase in extracts of Mycobacterium avium and Mycobacterium intracellulare.

A novel class of catalase, which differs from the previously described M- and T-catalases of mycobacteria, was detected in strains of Mycobacterium avium and M. intracellulare. Designated A-catalase, this enzyme resisted inactivation at 68 degrees C, was inactivated by 3-amino-1,2,4-triazole (aminotriazole), and exhibited no peroxidase activity. All of these properties distinguished the enzyme ...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 1987

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.25.9.1687-1690.1987